ISSN 2415-1297 (Online)   ISSN 2415-1300 (Print)
 
             
 
Volume : 27 Issue : 1 Year : 2019
 
Study of Analgesic and Anti Inflammatory Activity from Plant Extracts of Lactuca Scariola and Artemisia Absinthium [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. 1992; 5(2): 111-114

Study of Analgesic and Anti Inflammatory Activity from Plant Extracts of Lactuca Scariola and Artemisia Absinthium

Fayyaz Ahmad, Rafeeq A. Khan, Shahid Rasheed
From Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan.

Seeds and samples of stems from the two medicinal plants, Lactuca scariola and Artemisia absinthium respectively were extracted in absolute methanol to determine their analgesic and anti-inflammatory activity. The analgesic activity was assessed on intact mice by tail flick latency in tail immersion method. The anti-inflammatory activity was estimated volumetrically by measuring the mean increase in hind paw volume of rat with the help of plethysmometer. Acetylsalicylic acid in the dose of 300 mg/kg is used as standard drug. Both plant extracts were given in the doses of 300, 500 and 1000 mg/kg. Control group received 0.9% NaCI (saline) solution. All the doses administered orally. Results showed that Lactuca had potent analgesic activity and Artemisia had significant analgesic and anti-inflammatory activity.

Keywords: Lactuca scariola, artemisia absinthium, methanolic extract, analgesia, anti-inflammatory.


Fayyaz Ahmad, Rafeeq A. Khan, Shahid Rasheed. Study of Analgesic and Anti Inflammatory Activity from Plant Extracts of Lactuca Scariola and Artemisia Absinthium. Med J Islamic World Acad Sci. 1992; 5(2): 111-114

Corresponding Author: Rafeeq A. Khan, Pakistan


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